Another piece to the puzzle of what causes male pattern baldness has been discovered by a team of researchers at the University of Pennsylvania.
Through comparing bald areas of the scalp to harrier areas, a team of researchers lead by Dr. George Cotsarelis have found that a protein called prostaglandin D2 is found in much higher concentrations in the bald areas. When this protein was added to a sample of human hair follicles, the hair stopped growing.
Taking these findings further, the researchers studied the hair follicles of mice because they go through cycles of growth and regression that are similar to human hair follicles. The team found that prostaglandin D2 was at its highest levels right before the hair follicles entered the regression phase, suggesting that an over abundance of the protein could keep the follicle in the regression phase, preventing hair from growing.
Finding evidence to link prostaglandin D2 to baldness in both human and mice subjects makes this study more promising than other studies which have found clues to male pattern baldness in only non-human subjects. Dr. Cotsarelis explained,
“This is a much more targeted approach and much more likely to yield a treatment.”
Dr. Cotsarelis has been named one of America’s Leading Experts on Baldness (Alopecia) and is an author of over 50 academic publications.
Want to know more about Dr. Cotsarelis and how to schedule an appointment to see him? Visit his profile.
(Source: ABC News)