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October 27th, 2009

The Comeback of a Misunderstood Drug, LSD

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Dr. Albert Hoffman, founder of LSD and Psilocybin (flickr.com)

Dr. Albert Hoffman, founder of LSD and Psilocybin (flickr.com)

Getting high with a little help from your friends was a real trip in the 1960’s. This was not the intention of Albert Hofmann, the creator of the hallucinogenic drugs LSD and psilocybin. He’d hoped to explore its therapeutic uses. But they are finally back in the hands of the medical community, picking up where they left off.

In 1930’s Dr. Hofmann accidentally learned of LSD’s incredible side effects when he absorbed a small amount through his fingertips. He described a not unpleasant intoxicated-like feeling characterized by uninterrupted streams of fantastic pictures, extraordinary shapes and an intense, kaleidoscope of colors.

It was inevitable that this fantastical mind-altering drug became the center of the 1960’s drug-driven counterculture. To Hofmann’s dismay, it was placed into a restrictive category in the 1970’s by the U.S. Drug Enforcement Administration.

According to this month’s Scientific American, Albert Hofmann finally celebrated the first scientific research in decades one month before his death at the age of 102. Using psychedelic drugs for medical applications, such as treating alcoholism and alleviating intense anxiety for patients with life threatening diseases, are once again being explored.

The British-based Beckley Foundation is funding and collaborating on such a study at the University of California Berkley. They are assessing how these drugs may foster creativity and investigating the changes in neural activity that go along with altered conscious experiences, using Hofmann’s psilocybin instead of LSD.

“We chose psilocybin over LSD because it’s gentler and generally less intense,” says Dr. Charles S. Grob, a professor of psychiatry at the University of California, Los Angeles who conducted a trial to test the drug’s effects on anxiety in cancer patients.

“It’s associated with fewer panic reactions and less chance of paranoia and, most important, over the past half a century psilocybin has attracted far less negative publicity and carries far less cultural baggage than LSD.”

According to Vitals.com, Dr. Grob received his medical degree at the State University of New York Downstate College of Medicine and completed his specialty training at John Hopkins Hospital.

There had been similar experiments with LSD dating back over 35 years ago, but researchers are basically starting from scratch. LSD is still a trip, but navigated by a well programmed GPS that must meet strict drug protocols and standards.

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The Comeback of a Misunderstood Drug, LSD10.0105

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4 Comments

  1. visitor | October 27, 2009 at 12:53 pm

    Actually, it’s not correct to call Albert Hofmann the “creator” of psilocybin. While he was the first to synthesize the chemical in a laboratory, it occurs naturally in many species of mushrooms. He first identified psilocybin as the main active constituent of Psilocybe mexicana mushrooms, then found a way to synthesize it.

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  2. brad | October 28, 2009 at 9:54 pm

    Becasue of my personal experiences with LSD and Psilocybin I am shocked they chose psilocybin over LSD. I found LSD to be a calmer and cleaner trip while Psilocybin produced lots of anxiety for me. It must have to do more with the cultural baggage they were referring to.

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  3. dmt | October 29, 2009 at 11:02 am

    Its abotu time they do some legitimate scientific research on these substances!

    Too many lies have been spread by the US and other governments leaving many not knowing what to believe.

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  4. savedbytheShroom | October 30, 2009 at 10:40 am

    This is a new step that will lead us to the end of Prohibition. Which makes me really happy.

    Intensive trips with Psilocibine cured me from my serious alcohol problem.

    Magic Mushrooms are much safer than alcohol and nicotine.

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